Functional autoantibodies against G protein-coupled receptors in patients with persistent Long COVID 19 symptoms.

Zug, Switzerland, and Berlin, Germany, 19 April 2021

A new paper is published about Functional autoantibodies against G protein-coupled receptors in patients with persistent post COVID 19 symptoms. It can be downloaded from the publisher.

Highlights

  • Sera from Long COVID syndrome patients contained functionally active autoantibodies targeting G protein-coupled receptors.
  • Autoantibodies target β2- and α1-adrenoceptors, angiotensin II AT1-, muscarinic M2-, MAS-, nociceptin- and ETA-receptors.
  • Included syndromes were of neurological and cardiological origin, or a combination of both.
  • Such autoantibody patterns have previously been seen in COVID independent neurological deficits and cardiovascular disease.

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